Value of TI-RADS and elastography strain ratio in predicting malignant thyroid nodules: experience from a single center in Egypt

Abstract Introduction Thyroid nodules are highly prevalent in the general population; therefore, it is crucial to discriminate benign from malignant nodules. A practical thyroid imaging reporting and data system (TI-RADS) for ultrasound elastography valuable tools not only characterization of but also selection tumors fine-needle aspiration cytology (FNAC). Objective This study aimed evaluate diagnostic accuracy US evaluation prediction role score, strain ratio (SR), TI-RADS scoring as non-invasive differentiation between Material methods total 1269 patients were evaluated February 2017 April 2020 by a single expert operator. The final diagnosis was achieved cytological and/or histological follow-up at least 1 year. Results There 1088 females 181 males with mean age 44 ± 10 SD. 1197 72 Most scored score 4 (83.3%) category 5 (86.11%). We found that antero-posterior transverse (A-P/T) diameter > 1, have 21 times more risk be than those A-P/T < solitary 4.5 develop malignancy compared multinodular goiter (MNG), absent halo malignancy. Furthermore, microcalcifications increase 9 without calcifications. SR an excellent discriminator differentiate P 0.001. Also, we every unit SR, increased 20%. reported ultrasonography detection had sensitivity 89%, specificity 98%, 70% PPV, 99.3% NPV, overall 97.2%. Conclusion application ultrasonographic criteria clinical practice might significantly reduce number unnecessary FNAC. Elastography, classification could good predictors